Serum Cholesterol, Triglyceride, and Ghrelin Levels in Criminal and Non-criminal Schizophrenia Patients
نویسندگان
چکیده
Amaç: Suç kavram›, flahs›n yaflad›¤› toplumdaki mevcut hukuk düzenini bozan, toplumun ahlaki kurallar›n› ihlal eden ve kamunun menfaatine karfl› olan davran›fllar› içeren bir kavramd›r. Psikiyatrik hastal›klar içerisinde sald›rgan davran›fllarla iliflkili hastal›k olarak flizofreni dikkat çekmektedir. fiizofrenili hastalarda suç iflleme ve sald›rgan davran›fllar üzerinde baz› biyokimyasal parametre düzeylerinin etkili oldu¤u düflünülmektedir. Bu çal›flmada suç ifllemifl ve ifllememifl flizofrenili hastalarda serum kolesterol, trigliserit ve ghrelin düzeylerindeki fakl›l›klar karfl›laflt›r›larak suç üzerindeki etkilerinin de¤erlendirilmesi amaçlanm›flt›r. Yöntem: Çal›flma süresince Elaz›¤ Ruh ve Sinir Hastal›klar› Hastanesinde flizofreni tan›s› alm›fl ve tedavi gören en az bir suç kayd› olan 50 erkek flizofrenili hasta ile herhangi bir suç kayd› olmayan 50 erkek flizofrenili hasta araflt›rmaya al›nd›. Hastalara sosyodemografik bilgi formu uyguland›. Kan örnekleri, çal›flma kriterlerine uyan hasta ve kontrol gruplar›ndan sabah 08.00–11.00 saatleri aras›nda al›narak serum total kolesterol, trigliserid ve ghrelin düzeylerine bak›ld›. Bulgular: Suç ifllemifl flizofrenili hastalar ile suç ifllememifl flizofrenili hastalar karfl›laflt›r›ld›¤›nda; suç iflleyen flizofrenili hastalar›n serum trigliserit ve ghrelin düzeyleri, suç ifllememifl flizofrenili hasta grubuna göre daha yüksek bulundu. Aradaki fark trigliserit ve ghrelinde istatistiksel olarak anlaml›yd›. Serum total kolesterol düzeyleri ise suç ifllemifl olan flizofrenili hastalarda daha düflük olarak tespit edildi. Aralar›ndaki bu farkl›l›k istatistiksel olarak anlaml› bulunmad›. Tart›flma: Bulgular›m›z flizofrenili hastalarda suça yatk›nl›k konusunda baz› biyokimyasal parametrelerin düzeylerinin önemli oldu¤unu gösterdi. Suç ifllemede bu parametrelerin etkinli¤inin güvenilir bir flekilde kullan›labilmesi için daha ileri çal›flmalara ihtiyaç vard›r. Özellikle kolesterol ve ghrelin düzeylerinin belirlenmesinin suç iflleme e¤ilimi olan flizofreni hastalar›n›n tedavi ve de¤erlendirmelerinde klinisyenlere katk› sa¤layaca¤›n› düflünmekteyiz.
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